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  • SmartDrop Nano Spectrophotometers

    Microvolume Analysis of DNA, RNA and Proteins

    • Quick and accurate results from a sample droplet

    • Touch screen control panel, no PC or software required

    • Built-in printer and cuvette port for OD600 readings

    • XF model includes fluorometer for sensitive DNA





    The Accuris SmartDrop™ series of nano spectrophotometers provides quick and easy quantification of small samples. Utilizing a small sample volume eliminates the need for dilutions, providing more accurate results.

    A full color, 7” touchscreen with icon-driven menus and preprogrammed protocols gets users up and running quickly. No external computer is required. Each unit features a quartz pedestal onto which a drop of sample is placed. The arm is lowered and the drop is stretched into a liquid column of specificed length for spectral analysis. DNA, RNA and protein concentrations and purity numbers are displayed in a matter of seconds.

    The resulting data can be printed, saved in the SmartDrop’s onboard memory or exported via USB as an Excel file. All SmartDrop models include an integrated printer. For OD600 readings, each model includes a cuvette port and two optical glass cuvettes. Three SmartDrop models are available to meet a range of applications and budgets.





    SmartDrop XF with Fluorometer

    NS1020-T,  0.5mL Fluorescence Detection Tubes, pack of 250

    SmartDrop L

    • Ideal for basic DNA/RNA/protein quantification and purity
    • Affordable LED and silicon detector technology
    • Fixed 0.5mm path length, detect up to 2500ng/µl of dsDNA

    SmartDrop L is the affordable choice for laboratories needing to determine nucleic acid and protein concentrations and purity of samples. The LED light source and silicon photocell sensor provide readings at 260 and 280nm. Samples from 1.0 to 2.0µl are loaded directly on the pedestal. Results are provided in about 5 seconds. The software automatically
    calculates and displays 260/280 ratios.

    SmartDrop X

    • Full-spectrum absorbance scans from 200 to 800nm
    • Quickly calculates and displays 260/280 and 260/230 ratios
    • Long-life Xenon lamp with precision monochromator
    • Auto-ranging path lengths of 0.2mm and 1.0mm
    • Detect up to 4,500 ng/µl of dsDNA without dilution

    A full spectrum UV-Vis spectrophotometer, SmartDrop X requires 0.5 to 2.0µl of sample. In addition to nucleic acid and protein calculations, the software has preset programs for BCA, Bradford and Lowry assays. A full spectrum analysis can be performed in about 6 seconds, aiding in the
    identification of unknowns. Up to 5 specific points on the spectrum can be selected for colorimetric readings output. The long life Xenon lamp source requires no warm up and is paried with a highly sensitive CCD detector. To provide the most accurate results, the
    SmartDrop X utilizes 2 path lengths.

    SmartDrop XF – Spectrophotometer + Fluorometer

    • Full-spectrum absorbance scanning and calculations of
      260/280 and 260/230 ratios
    • Long-life Xenon lamp with precision monochromator
    • Auto-ranging path lengths of 0.05mm, 0.2mm and
    • Detect up to 15,000ng/µl of dsDNA without dilution
    • Integrated fluorometer for sensitive quantitation of low
      concentration nucleic acids

    This top of the line spectrophotometer can perform not only UV-Vis readings in the range of 200-800nm but also fluorescence readings. Like the SmartDrop X, the SmartDrop XF features predefined programs for nucleic acids, proteins, and various colorimetric assays. The patented, motorized system gently stretches the sample column and allows for three different path lengths, providing accurate readings of samples from 0.5 to 2.0µl without dilution.
    The integrated fluorometer yields more accurate, sensitive and selective quantitation of nucleic acids. The blue light channel (460nm) is useful for detection of dyes such as PicoGreen and RiboGreen as well as GFP and fluorescein. UV, green and red channel models are available upon



    ModelSmartDrop L (NS1000)SmartDrop X (NS1010)SmartDrop XF (NS1020)
    Display7-inch touch screen7-inch touch screen7-inch touch screen
    Minimum sample size1.0µl – 2.0µl0.5µl – 2.0µl0.5µl – 2.0µl
    Path length0.5mm0.2mm, 1.0mm0.05mm, 0.2mm, 1.0mm
    Light sourceUV LEDXenon Flash LampXenon Flash Lamp
    DetectorUV Silicon Photocell2048 Element Linear Silicon CCD Array2048 Element Linear Silicon CCD Array
    Wavelength260, 280, & 600nm200 – 800nm (1nm steps)200 – 800nm (1nm steps)
    Absorbance range0.2 – 50 A (10mm equivalent)0.04 – 90 A (10mm equivalent)0.04 – 300 A (10mm equivalent)
    Absorbance precision0.005 A0.003 A0.003 A
    Lower limit of detectiondsDNA: 10ng/µldsDNA: 2ng/µl; BSA: 0.1mg/mldsDNA: 2ng/µl ; BSA: 0.1mg/ml
    Upper limit of detectiondsDNA: 2,500ng/µldsDNA: 4,500ng/µl; BSA: 135mg/mldsDNA: 15,000ng/µl; BSA: 360mg/ml
    Detection time< 6 seconds< 5 seconds< 6 seconds
    Communication portsUSB for data exportUSB for data exportUSB for data export
    Voltage inputDC 24V, 2ADC 24V, 2ADC 24V, 2A
    Dimensions (WxDxH)20.8 x 8.0 x 18.6 cm / 8.2 x 11.0 x 7.3 in.20.8 x 8.0 x 18.6 cm / 8.2 x 11.0 x 7.3 in.20.8 x 8.0 x 18.6 cm / 8.2 x 11.0 x 7.3 in.
    Weight3.6 kg / 7.9 lbs2.8 kg / 6.2 lbs3.6 kg / 7.9 lbs
    Cuvette OD600 detection
    Absorbance range0.0 – 4.0 A0.0 – 4.0 A0.0 – 4.0 A
    Absorbance stability[0,3) ≤ 0.5%, [3,4) ≤ 2%[0,3) ≤ 0.5%, [3,4) ≤ 2%[0,3) ≤ 0.5%, [3,4) ≤ 2%
    Absorbance repeatibility[0,3) ≤ 0.5%, [3,4) ≤ 2%[0,3) ≤ 0.5%, [3,4) ≤ 2%[0,3) ≤ 0.5%, [3,4) ≤ 2%
    Absorbance precision[0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2%[0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2%[0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2%
    Fluorescence detection
    Excitation/EmissionN/AN/A460 ± 20nm / 525-570nm
    SensitivityN/AN/AdsDNA: 0.5pg/µl
    LinearityN/AN/AR² ≥ 0.995
    RepeatibilityN/AN/A≤ 1.5%
    StabilityN/AN/A≤ 1.5%

    Ordering Information:

    Cat No.Description
    NS1000*SmartDrop™ L Nano Spectrophotometer, 115V
    NS1010*SmartDrop™ X Nano Spectrophotometer, 115V
    NS1020*SmartDrop™ XF Nano Spectrophotometer, 115V
    NS1020-HS-100High Sensitivity DNA Quantification Kit, 100 assays
    NS1020-BR-100Broad Range dsDNA Quantification Kit, 100 assays
    NS1020-T0.5mL Fluorescence Detection Tubes, pack of 250
    NS1000-CAdditional Standard-Size Cuvettes, pack of 2
    NS1000-PAExtra paper roll for SmartDrop internal printer, Pk 3

    Links and Download Documents

  • User Manual (SmartDrop XF)
  • Product Brochure